Fullmetal Alchemist: Brotherhood director Yasuhiro Irie has confirmed via his Twitter account on Thursday that Hiromu Arakawa has planned out the final installment of her long-running manga, Fullmetal Alchemist and his staff is now busy storyboarding the material for the anime. He added that he was shocked on the enormity of the final chapter and they have two months left.
Source: Anime News Network, csakuras
Based on the information that I paraphrased, I will really expect an explosive end for FMA: Brotherhood. Hope that it is more explosive than the first one!